Dipika Kakar, an Indian actor, is currently facing a relapse of liver cancer and has lost 2 kg over the past month by adhering to a strict diet. Doctors highlight that nutrition and lifestyle are critical for the success of immunotherapy, which activates the body's immune system to combat cancer. Dr. Eileen Canday, Head of Nutrition & Dietetics at Sir HN Reliance Foundation Hospital in Mumbai, explains that the immune system requires energy and nutrients to function effectively, and poor nutrition can weaken it. Cancer can lead to cachexia, a condition that causes muscle loss despite adequate food intake, making tailored nutrition essential for treatment efficacy. Dr. Nitin Bayas from M|O|C Cancer Care and Research Centre emphasizes that patients receiving nutrition counseling alongside immunotherapy tend to respond better. New approaches like nutrigenomics and metabolomics are being used to customize diets based on individual needs. A diverse gut microbiome has been linked to stronger immune responses, and patients are advised to consume high-quality proteins and essential micronutrients to support their health during treatment. Maintaining a healthy weight is also crucial, as obesity is linked to higher risks of cancer recurrence.