Marty Makary resigned from his position as Commissioner of the Food and Drug Administration (FDA) after facing pressure from the Trump administration to approve fruit-flavored e-cigarettes. His resignation comes just days after reports surfaced about plans for his ouster, which were linked to his resistance against the approval of these products due to concerns over youth addiction. President Trump confirmed Makary's resignation on social media, praising his contributions to the FDA and stating that he would have a successful career in medicine. This situation underscores the ongoing conflict between public health priorities and the interests of the tobacco industry, as the administration's push for e-cigarette approvals aligns with Trump's campaign promise to support vaping. Kyle Diamantas, the FDA's top food regulator, has been appointed as the acting commissioner in the interim.