Mosquito-borne diseases such as dengue and malaria are on the rise in India, making mosquito repellent creams vital for protection. Dermatologists like Dr. Priyanka Kuri from Aster Whitefield Hospital affirm that commonly used ingredients such as DEET, picaridin, and IR3535 are safe when applied as directed. However, they caution that individuals with sensitive skin may experience mild irritation. Dr. Sai Lahari Rachumallu from Manipal Hospital highlights that most adverse reactions stem from misuse rather than the products themselves. Proper application techniques, such as avoiding broken skin and washing off repellents after use, can minimize side effects. While natural alternatives may seem appealing, they often lack effectiveness and can also cause skin reactions. Ultimately, the consensus among dermatologists is that the health risks associated with mosquito-borne illnesses far outweigh the potential side effects of repellents. In a context where prevention is crucial, the real question is whether individuals can afford to forgo using repellents.