The Africa Centres for Disease Control and Prevention (Africa CDC) and the World Health Organization (WHO) have launched a joint preparedness and response plan to combat the ongoing Ebola outbreak caused by the Bundibugyo virus. The initiative seeks to raise $518 million to assist African nations in preparing for and responding to the outbreak over a six-month period from June to November 2026. This plan promotes a unified 'One Response' strategy that includes emergency coordination, disease surveillance, laboratory testing, and community engagement. Dr. Tedros Adhanom Ghebreyesus, WHO Director-General, emphasized the importance of speed and unity in the response, stating that the plan provides a clear path for action. Additionally, the initiative aims to protect vulnerable populations and enhance cross-border collaboration while maintaining support for other ongoing health emergencies such as mpox, cholera, and measles. The successful implementation of this plan will require strong political commitment and collaboration among governments, health workers, and communities to effectively control the outbreak and safeguard public health across the region.