Three people have died following a suspected Hantavirus outbreak on the MV Hondius cruise ship, which was traveling from Argentina to Cape Verde with approximately 150 passengers. The World Health Organization (WHO) reported one confirmed and five suspected cases of this rare disease. Hantavirus infections occur primarily through contact with infected rodent urine, droppings, or saliva, and can also be contracted by inhaling contaminated air, particularly in closed spaces. Symptoms often mimic those of common viral infections, making diagnosis challenging. According to Dr. Shilpa Singi, a lead consultant at Aster Whitefield Hospital in Bangalore, patients may experience fever, fatigue, muscle aches, and gastrointestinal symptoms. The disease can progress rapidly, leading to severe respiratory distress and a 40% fatality rate for Hantavirus Pulmonary Syndrome (HPS). Currently, there is no effective antiviral treatment, and medical care focuses on supportive measures. To reduce risk, experts recommend avoiding areas with rodent infestations and practicing good sanitation, including wearing protective gear when cleaning contaminated spaces.