In a recent talk at the Stanford Graduate School of Business, Daniela Amodei, president of Anthropic, shared her unconventional advice for selecting a cofounder: take a vacation together. Amodei emphasized that sharing a hotel room can expose potential weaknesses in the relationship, which is vital for a successful startup partnership. She humorously noted that if one feels the need for a vacation to recover from the vacation, it could signal a mismatch. Amodei, who co-founded Anthropic after leaving OpenAI with her brother Dario, highlighted the importance of being on the same page regarding core principles. She illustrated this by asking the audience to imagine drawing a picture of their startup while locked in separate rooms; differing visions could lead to significant issues down the line. Ultimately, Amodei's advice underscores that interpersonal dynamics matter greatly in the startup world.