A recent study led by researchers at the University of California San Diego has demonstrated that Mindfulness-Oriented Recovery Enhancement (MORE) can effectively reduce cravings and improve emotional well-being in individuals suffering from opioid use disorder (OUD). Published in the Journal of the American Medical Association, the study involved 160 participants who underwent MORE therapy, which combines mindfulness training, cognitive behavioral therapy, and positive psychology. Results indicated that those who completed the MORE program experienced a 50% reduction in opioid cravings compared to those receiving standard group therapy. This therapy works by restoring the brain's ability to savor natural rewards, which is often diminished in individuals with OUD. Previous studies have shown that MORE can decrease opioid misuse by 45% over nine months and significantly reduce chronic pain. The economic benefits are also noteworthy, with a projected $798 return for every dollar spent on MORE, leading to a lifetime economic impact of $320,216 per person treated. The research underscores the need for broader implementation of this evidence-based therapy to combat the opioid crisis effectively.