Unintentional weight loss, which is defined as losing more than 5-10% of body weight over 6 to 12 months without effort, can be a significant warning sign of underlying health issues, including cancer. Dr. Arvind Kumar, a senior medical oncologist at the All India Institute of Medical Sciences (AIIMS) in New Delhi, explains that in certain cancers, the body’s metabolism changes, causing cancer cells to consume large amounts of energy and depleting the body's resources. Conditions such as loss of appetite, nausea, and digestive issues may also contribute to this weight loss. While unexplained weight loss can be alarming, it is essential to note that it does not always indicate cancer; other factors such as infections, stress, and thyroid disorders can also be responsible. Individuals experiencing symptoms like persistent fatigue, loss of appetite, or unusual pain should not ignore these signs. Early detection through medical check-ups, blood tests, or imaging can significantly enhance treatment outcomes. Recognizing and acting on these subtle changes in your body is crucial for maintaining health.