Mosquito-borne diseases such as dengue and malaria remain a significant public health challenge in India, prompting many to rely on mosquito repellent creams for protection. Dermatologists, including Dr. Priyanka Kuri from Aster Whitefield Hospital in Bengaluru, assert that these creams are safe when used correctly, with well-studied ingredients like DEET, picaridin, and IR3535. Although some users may experience mild skin reactions, such as irritation or redness, these are generally rare and often linked to misuse, such as overapplication or applying on damaged skin. Experts emphasize that the risk of contracting mosquito-borne diseases is far greater than the potential for skin irritation. They recommend applying the correct amount, avoiding sensitive areas, and washing off the product after use. The consensus among health authorities, including the World Health Organization (WHO), is that mosquito repellents are a crucial strategy for preventing serious infections. Therefore, proper usage is essential to maximize benefits while minimizing risks.