During her presentation at the Fortune COO Summit, Dr. Deepika Chopra, a clinical health psychologist and behavioral scientist, addressed the psychological aspects of resistance to artificial intelligence (AI) adoption. She argued that the challenges faced by leaders are often misinterpreted as resistance when they are actually normal human responses to uncertainty. Chopra explained that when faced with unknowns, the brain's threat-detection system activates, causing individuals to cling to familiar practices. She emphasized that the questions surrounding AI adoption are fundamentally human, focusing on individuals' concerns about their value and contributions in the workplace. To navigate these challenges, Chopra proposed three actionable strategies for leaders: create clarity to combat confusion, foster adaptability rather than seeking certainty, and recognize the importance of meaning and purpose during disruptive changes. Her insights highlight the need for leaders to address the psychological dimensions of change management in the context of AI implementation.