The Ebola outbreak in Central Africa is escalating, with nearly 500 confirmed cases reported. The World Health Organization (WHO) has confirmed 452 cases and 82 deaths in the Democratic Republic of the Congo (DRC), alongside 19 cases and 2 deaths in Uganda. This marks a significant increase of 100 cases and 20 deaths in just one day, raising alarms about the potential for the outbreak to become the largest on record. Declared an international public health emergency, the outbreak began on May 15, 2023, and is attributed to the rare Bundibugyo species of Ebola, for which there are currently no approved vaccines or treatments. In response, the WHO and the African CDC have initiated a $518-million plan aimed at enhancing surveillance, laboratory testing, and infection control measures. WHO chief Tedros Adhanom Ghebreyesus emphasized the urgency of stopping the outbreak and supporting affected countries to prepare for potential cases in neighboring regions. Health officials warn that without robust public health interventions, the outbreak could escalate to levels comparable to the 2014 West Africa epidemic, which resulted in over 28,000 cases and more than 11,000 deaths.