Health officials in Ludhiana, Punjab, India, have reported a consistent rise in HIV detections, primarily linked to intravenous drug use, unprotected sexual practices, and interruptions in treatment adherence. At the civil hospital's anti-retroviral therapy (ART) centre, nearly 100 individuals are screened daily, with new positive cases emerging weekly. The rise is closely tied to the sharing of contaminated syringes among drug users, which remains a significant transmission risk. Additionally, the high mobility of Ludhiana's migrant workforce complicates treatment efforts, as many individuals discontinue therapy upon relocating for work. Stigma associated with HIV further hinders containment, leading to delayed diagnoses and interventions. To address these challenges, health authorities are focusing on targeted interventions for high-risk groups, including drug users and sex workers. The district estimates the HIV prevalence at approximately 0.42%, though the actual number may be higher due to undiagnosed cases. The health department is intensifying the global '95-95-95' strategy, aiming to ensure that 95% of HIV-positive individuals are diagnosed, treated, and achieve viral suppression, emphasizing that lifelong treatment is essential for those infected.