On World Liver Day, Dr. Sonal Asthana, Lead Consultant in HPB & Liver Transplant Surgery at Aster RV Hospital, warns about the dangers of excessive painkiller and supplement use leading to liver damage. The liver, vital for detoxifying substances, can be overwhelmed by high doses of medications like paracetamol, which is a leading cause of acute liver failure globally. Many individuals mistakenly believe that 'natural' or herbal supplements are safe, but these can also contain harmful ingredients and heavy metals. Self-medication is a growing concern, as people often turn to over-the-counter medications for persistent pain or fatigue without professional advice. Symptoms of liver damage can be subtle initially but may progress to severe conditions like jaundice and abdominal swelling. Fortunately, most drug-related liver damage is preventable through awareness and responsible medication practices. Regular health evaluations, including liver function tests, are essential for those who frequently use medications and supplements. Ultimately, maintaining liver health requires informed choices and a thorough understanding of the risks associated with improper medication use.