Fortis Life Sciences has introduced the AbNano® VHH Anti-NK Cell Library, a groundbreaking resource for antibody discovery derived from peripheral natural killer (NK) cells. This library is designed to tackle the complexities associated with NK-cell receptor systems, which present significant challenges due to their intricate nature and varied expression patterns. The compact single-domain antibodies (VHHs) in this library are particularly advantageous for targeting difficult-to-access NK-associated receptors. Validation studies have demonstrated the library's effectiveness in identifying binders for several key NK targets, including CD56, CD8a, and NKp46, thereby supporting diverse biological functions. Chris Woodward, senior director of antibody solutions at Fortis, emphasized that this specialized repertoire can significantly enhance the efficiency of identifying immune targets, potentially expediting the development of engineered immune cell therapies for cancer and complex immune disorders. The AbNano library is the third addition to Fortis's growing portfolio and is available as a standalone product or through custom discovery services, which include comprehensive support for antibody development workflows.