Health authorities are responding to a hantavirus outbreak associated with the MV Hondius cruise ship, which has confirmed five cases and resulted in three deaths. The World Health Organization (WHO) noted that the Andes strain of hantavirus, identified in some patients, is capable of limited human-to-human transmission. The ship had 147 individuals onboard, including 88 passengers and 59 crew members from 23 nationalities. Authorities in countries such as South Africa, the Netherlands, Switzerland, Spain, and the United States are tracing passengers and contacts who may have been exposed. The first known patient, a 70-year-old Dutch man, fell ill on April 6 and died on April 11. His wife also succumbed to the virus later, and a German woman died on May 2 under similar circumstances. The WHO has advised all passengers and crew to monitor for symptoms for 45 days, as there is currently no vaccine or specific treatment available for hantavirus, although early intensive care can improve survival chances.