New Biological Clock Developed to Estimate Lifespan
Scientists Created a New Biological Clock That Reveals How Much Time You Have Left
Vice News
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Researchers have created a 'transcriptomic clock' that measures biological age by analyzing gene activity, providing insights into mortality risk. This tool, based on gene expression patterns from over 11,000 samples across species, could revolutionize how we understand aging and its impact on health.
- 01The 'transcriptomic clock' analyzes RNA to determine biological age and expected mortality risk.
- 02The study involved over 11,000 samples from mice, rats, macaques, and humans.
- 03Gene expression patterns linked to healthy cell division indicate slower aging, while those tied to inflammation suggest faster aging.
- 04Similar gene patterns were observed across different species and organs, indicating a shared biological framework for aging.
- 05This tool could help assess the effects of diseases, medications, and lifestyle choices on biological aging.
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A team of researchers has developed a groundbreaking tool known as the 'transcriptomic clock,' which measures biological age through gene activity analysis. Published in the journal Nature, this study utilizes gene expression patterns from over 11,000 samples across four species: mice, rats, macaques, and humans. The clock identifies distinct signatures of aging, revealing that genes associated with healthy cell division correlate with slower biological aging, while those linked to inflammation and cell death are associated with accelerated aging. Remarkably, the same age-related genes were found in rat livers and human hearts, suggesting a common biological framework for aging across species. This innovative tool not only estimates lifespan but also has the potential to evaluate how diseases, medications, and lifestyle choices influence biological aging, allowing researchers to observe effects without waiting years for outcomes.
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The development of the transcriptomic clock could significantly influence health research and personal health management.
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