The University of Wisconsin-Madison's College of Engineering is launching six Engineering Moonshots, which are bold, transdisciplinary initiatives designed to tackle significant societal challenges. This strategic focus aims to foster collaboration across various fields, leveraging the strengths of engineering and other disciplines to create impactful solutions. The initiative aligns with the university's strategic priorities and embodies the Wisconsin Idea, emphasizing the importance of extending knowledge and resources outward for community benefit. Over the next few months, the college will transition these Moonshots from concept to execution, appointing engineering leads and co-leads from diverse backgrounds. The university has already invested in its RISE initiative, hiring new faculty to support this endeavor, and plans to expand opportunities for both graduate and undergraduate students to engage in real-world challenges. By fostering partnerships with universities, industry, and national laboratories, UW-Madison aims to translate discoveries into practical solutions that benefit society.