ABC is expanding the 'Grey's Anatomy' franchise with a new spin-off set in a rural hospital in West Texas. The untitled series, co-created by Shonda Rhimes and Meg Marinis, aims to capture the heart and emotion that fans have come to love over the past two decades. Marinis, a Houston native and University of Texas at Austin graduate, expressed her excitement about bringing new characters and stories to life in her home state. This spin-off will be unique as it will not feature any main cast members from the original series, making it the first to do so. However, it will maintain connections to the Grey's Anatomy universe, potentially including characters like Dr. Catherine Fox, played by Debbie Allen. The show is set to premiere in mid-2027, marking a significant addition to the franchise, which already includes 'Private Practice' and 'Station 19'. Additionally, another rural Texas medical drama is in development by CBS, indicating a growing interest in this genre.