The hantavirus outbreak associated with the MV Hondius cruise ship has raised health concerns globally, resulting in three deaths and multiple infections across South Africa, the Netherlands, and Switzerland. The outbreak began in April 2026 after the ship departed from Argentina. The Andes strain of hantavirus is particularly alarming due to its limited human-to-human transmission potential in confined spaces. Hantavirus is primarily contracted through aerosolized rodent urine, droppings, or nesting materials, with symptoms appearing 1 to 8 weeks post-exposure. Early symptoms resemble flu-like conditions, while late-stage symptoms can lead to severe respiratory distress. Experts emphasize that even a single infected rodent can transmit the virus, making all wild rodents potential carriers. Although the risk in India remains low, experts warn that factors such as poor sanitation and rodent infestations could heighten exposure risks in certain areas.