In the fourth round of the 2026 French Open, Aryna Sabalenka, the top seed, will challenge Naomi Osaka, the 16th seed. Sabalenka is aiming for her first title at Roland Garros after a commanding start to the tournament, winning all her matches in straight sets and dropping only 18 games. Meanwhile, Osaka, a four-time Grand Slam champion, is experiencing a career revival and has reached the fourth round for the first time in her history at this event. She achieved this milestone by defeating No. 17 Iva Jovic in a hard-fought match. The odds heavily favor Sabalenka at -503, while Osaka stands at +368. Their past encounters in 2026 show Sabalenka winning both matches, but Osaka's recent form suggests she could pose a challenge. Betting enthusiasts might consider wagering on Osaka to win a set while Sabalenka ultimately takes the match, with odds at +290.