Over the past weekend, Moncton, New Brunswick, experienced a significant spike in suspected overdoses, with emergency responders reporting 65 overdose calls in just 72 hours. This surge is believed to be linked to the presence of medetomidine, a potent veterinary tranquilizer, mixed with fentanyl in the local drug supply. Moncton fire Chief Conrad Landry noted that his department responded to 52 overdose calls, a drastic increase from the usual four to five daily. Josue Goguen, a supervisor at the harm reduction organization Ensemble, reported that Friday was the worst day for overdoses since the organization opened its supervised consumption site five years ago. Many individuals were found in heavy sedation, and naloxone, which typically reverses opioid overdoses, was less effective against the tranquilizer. Despite a general downward trend in overdose calls in recent years, this weekend's events have raised concerns about the unpredictability of the drug supply. The Moncton fire department plans to introduce a smaller emergency response vehicle in July to alleviate pressure on resources.