Modern agricultural practices have diminished the nutrient density of foods, leading many individuals to rely on dietary supplements. However, this can pose health risks, particularly when overdosing occurs. For instance, excess Vitamin D can cause nausea, vomiting, and serious complications in the kidneys and heart due to increased calcium levels in the bloodstream. Similarly, taking calcium supplements without monitoring Vitamin D and magnesium can result in harmful calcifications. High doses of Vitamin E may increase oxidative stress, while prolonged intake of Vitamin A beyond 10,000 IU can lead to toxicity. Iron supplements, if taken without proper monitoring, can result in hemochromatosis, damaging internal organs. Experts, including Dr. Anoop Misra, emphasize that supplements should be guided by a healthcare professional, particularly for individuals with specific health conditions. For most people, a balanced diet rich in fruits, vegetables, and natural food sources can provide adequate nutrients without the need for supplements.