The EuroPCR 2026 conference highlighted a significant meta-analysis examining the role of coronary revascularization in patients with severe aortic stenosis (AS) and coronary artery disease (CAD) undergoing transcatheter aortic valve implantation (TAVI). Conducted by Roberto Scarsini, the ARTICA meta-analysis analyzed data from 1,050 patients, comparing outcomes between those who underwent FFR-guided PCI, angiography-guided PCI, and optimal medical treatment (OMT). The results indicated that PCI was associated with a 30% lower risk of major adverse cardiac events (MACE) at one year compared to OMT, primarily due to a reduced need for any revascularization. Notably, FFR-guided PCI demonstrated a 42% lower risk of MACE and also showed improved outcomes for net adverse clinical events (NACE). In contrast, angiography-guided PCI did not yield significant advantages over OMT. Furthermore, the study reported major bleeding rates of 8.2% for FFR-guided PCI, compared to 13.7% for angiography-guided PCI and 12.6% for OMT. These findings suggest that routine PCI may offer limited benefits, while physiology-guided approaches could enhance patient outcomes in this population.