Republican Senator John Kennedy has broken ranks with President Donald Trump, criticizing his recent attacks on Pope Leo XIV, which Kennedy described as a 'new holy war.' During a Fox News interview, Kennedy, a longtime ally of Trump, expressed his disagreement with Trump's comments, emphasizing his respect for Catholicism and questioning why there should be conflict with the Pope. This dispute arises amid escalating tensions over the U.S.-Israel conflict with Iran, where Pope Leo XIV condemned Trump's warning that 'a whole civilization will die' if Iran does not lift its blockade of the Strait of Hormuz. The Pope labeled Trump's comments as 'truly unacceptable' and highlighted that targeting civilian infrastructure violates international law. In response, Trump called the Pope 'WEAK on Crime' and criticized his foreign policy stance. Vice President JD Vance defended Trump, suggesting that religious and political leaders should maintain their respective roles. Despite the ongoing tensions, Pope Leo XIV clarified that he did not seek a prolonged exchange with the Trump administration and expressed no fear regarding the current political climate.