At the European Congress on Obesity in Istanbul, Dr. Michael Yafi, a children's medic at the University of Texas Houston, discussed how future art might reflect changing beauty standards influenced by the use of weight loss injections like GLP-1. He posits that women in upcoming masterpieces could appear 'gaunt and tired', contrasting sharply with historical representations, such as the Mona Lisa, who is believed to have been overweight and possibly suffering from high cholesterol or hypothyroidism. Dr. Yafi noted that in the past, obesity was often seen as a sign of beauty and prosperity, with many artists depicting women with fuller figures. He emphasized that the current trend towards extremely thin models is unhealthy and suggests that the rapid fat loss associated with weight loss jabs can lead to an aged appearance, particularly in the face. He speculated that if Picasso were alive today, he would likely capture these modern beauty ideals in his artwork. The Mona Lisa, completed in the early 1500s, remains one of the most iconic paintings, valued at approximately £1 billion today.