The Philadelphia 76ers and Boston Celtics faced off four times during the regular season, with both teams winning two games each. The first matchup on October 22, 2025, showcased rookie VJ Edgecombe, who scored 34 points in his debut, alongside Tyrese Maxey, who contributed 40 points to lead the Sixers to a narrow 117-116 victory. The second game on October 31 saw the Celtics take a 109-108 win, benefiting from a strong start, despite Maxey's 26 points. On November 11, the Sixers edged out the Celtics 102-100, with Justin Edwards stepping up with 22 points in the absence of Joel Embiid. However, in their final regular season meeting on March 1, 2026, the Celtics overwhelmed the Sixers 114-98, with Neemias Queta leading Boston with a career-high 27 points and 17 rebounds. This series of matchups sets an exciting backdrop for their playoff encounter starting Sunday.