In a disappointing performance, the Toronto Blue Jays lost 7-3 to the Los Angeles Angels at Angel Stadium in Anaheim, California, on April 22, 2026. The Jays struggled against Angels pitcher Jose Soriano, who maintained a shutout through five innings, despite the Jays managing seven hits. They failed to advance a runner past first base until the sixth inning, when they finally broke the scoring drought. Eric Lauer, pitching for the Jays, started well but faced difficulties in the third inning, leading to the Angels scoring three runs. The Angels capitalized on the Jays' pitching mistakes, with Nolan Schmanuel and Mike Trout hitting home runs. The Jays' late-game efforts, including a couple of runs in the sixth inning, were not enough to overcome the deficit. The team will have a brief break before returning home to face the Cleveland Guardians, with Gavin Williams scheduled to pitch against Max Scherzer.