Philip Morris International, known for selling Marlboro cigarettes outside the U.S., has revised its annual profit forecast downwards due to regulatory uncertainties regarding its Zyn nicotine pouches and increased competition from brands like British American Tobacco's Velo. Despite this forecast adjustment, the company's shares rose nearly 3% in premarket trading after it reported first-quarter revenue of $10.15 billion, surpassing analysts' expectations of $9.91 billion. The adjusted profit for the quarter was $1.96 per share, beating estimates of $1.83. However, Zyn shipment volumes in the U.S. dropped by 23.5%, reflecting challenges in the market. Philip Morris anticipates full-year adjusted earnings per share to be between $8.36 and $8.51, slightly above analyst expectations, while also considering a minor impact from the ongoing conflict in the Middle East.