The Denver Broncos will face the Kansas City Chiefs on September 14 in the inaugural Monday Night Football game of the 2026 NFL season. This matchup is significant as the Broncos dethroned the Chiefs from the AFC West title last season, ending Kansas City's nine-year dominance in the division. The game location will be announced when the NFL reveals the complete schedule. A key point of interest is the health of Chiefs quarterback Patrick Mahomes, who is recovering from a torn ACL and LCL sustained in December. Mahomes aims to be ready for the season opener, but his status remains uncertain. Meanwhile, Broncos quarterback Bo Nix, who broke a bone in his right ankle during the AFC playoffs, is expected to be fit for training camp. The NFL is set to announce more matchups in the coming days, including other notable games featuring teams like the Dallas Cowboys and Buffalo Bills.