As temperatures in Arizona soar to around 105 degrees Fahrenheit, the use of common allergy medications can pose additional risks. Certain antihistamines, particularly diphenhydramine, can inhibit the body's ability to sweat, which is crucial for cooling down. The Centers for Disease Control and Prevention (CDC) highlights that reduced sweating can make it challenging for the body to regulate heat during prolonged exposure to high temperatures. Additionally, medications like cetirizine (Zyrtec) and loratadine (Claritin) can lead to photosensitivity, resulting in adverse skin reactions such as redness or rashes. Although not everyone will experience these side effects, the Food and Drug Administration (FDA) recommends that individuals check medication labels for warnings regarding heat and sunlight. To mitigate risks, people are advised to limit outdoor activities during peak sunlight hours, wear protective clothing and sunscreen, and consult healthcare professionals about their medications. A pharmacist notes that reviewing allergy medications at the start of the hottest months is prudent to ensure safety during extreme heat.