Life Biosciences Initiates Human Trials for Vision Restoration Drug
Longevity Startup Doses First Human in Bid to Reverse Age-Related Sight Loss

Image: Wired
Life Biosciences has begun testing its ER-100 drug on 18 adults to assess its safety and side effects. The drug aims to restore vision in patients with glaucoma and NAION by rejuvenating damaged optic nerve cells, marking a significant advancement in cellular rejuvenation therapy.
- 01ER-100 has previously restored vision in monkeys and is now in human trials.
- 02The study will involve approximately 18 adults over the next year to evaluate safety and side effects.
- 03This is the first cellular rejuvenation therapy to receive FDA clearance for human trials.
- 04The drug targets patients suffering from glaucoma and NAION, which damage optic nerve cells.
- 05Life Biosciences aims to address various age-related diseases beyond vision loss, including fatty liver disease.
Advertisement
In-Article Ad
Life Biosciences has initiated human clinical trials for its innovative drug ER-100, which aims to restore vision in individuals suffering from glaucoma and non-arteritic anterior ischemic optic neuropathy (NAION). This groundbreaking therapy, which has shown promise in restoring vision in monkeys, is now being tested for safety and side effects in a study involving around 18 adults over the next year. ER-100 is notable for being the first cellular rejuvenation therapy to gain FDA approval for human trials, representing a potential breakthrough in longevity science. According to David Sinclair, co-founder of Life Biosciences and a professor of Genetics at Harvard Medical School, the study will explore whether restoring epigenetic information can improve human health by rejuvenating damaged cells in the optic nerve. This research is pivotal as it delves into the biology of aging and its effects on cellular function. Life Biosciences, based in Boston, is also exploring the application of its technology to combat other age-related diseases, indicating a broader ambition to address the challenges posed by aging across various organ systems.
Advertisement
In-Article Ad
The clinical trial could lead to new treatment options for age-related vision loss, significantly impacting patients with glaucoma and NAION.
Advertisement
In-Article Ad
Reader Poll
What do you think about the potential of cellular rejuvenation therapies?
Connecting to poll...
Read the original article
Visit the source for the complete story.





