During the week of May 18-22, large-cap stocks, particularly in the technology and healthcare sectors, experienced notable declines as investors reacted to a confluence of factors including weak earnings guidance, regulatory concerns, and rising bond yields. Intuit Inc. (NASDAQ:INTU) led the losses, plummeting 18.28% after it reported disappointing third-quarter financial results and announced a 17% reduction in its workforce. NIO Inc. (NYSE:NIO) followed closely, decreasing 12.58% amid negative sentiment surrounding U.S.-listed Chinese companies, particularly after the China Securities Regulatory Commission's announcement to crack down on illegal cross-border securities trading. Other significant losers included Pershing Square Inc. (NYSE:PS), which dropped 13.9%, and Tenet Healthcare Corporation (NYSE:THC), down 12.46%. The overall market sentiment was further dampened by increasing bond yields, which negatively impacted data center-related companies and their funding outlook. As investors reassess their portfolios, these declines raise questions about the future performance of these large-cap stocks.